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The U.S. Food and Drug Administration has approved Contrave (naltrexone hydrochloride and bupropion hydrochloride extended-release tablets) as treatment selection for chronic weight reduction in addition to a reduced-calorie diet and physical activity.

Using two separate drugs to lose weight can be very effective there are combinations before the FDA now awaiting approval. When dealing with fat loss and the individuals who go through it you need to err to the side of caution and permit the FDA do its job and demand some research be done so the public understands the side effects and dangers of the medications before we take them. Keep in mind that drug companies come in business to generate money and that they would say almost anything to keep people on the medications.

Researchers discovered that participants investing in this drug for the year, dropped a few pounds within 4 weeks and have kept the weight off throughout the 56 weeks from the study. Contrave is often a combination of the drugs naltrexone and bupropion, which seems to reflect a whole new trend of weight-loss drugs which might be made up of many active ingredient, which may make them far better and safer.

Combo-pilling could be the newest fad or also the newest into the future under scrutiny and therefore it is just more publicly known recently, comb-pilling for weight loss has been around since the eighties. The biggest reason that using a combination of pills is becoming popular is the fact that by right now there are not any long term prescription weight loss supplements that have been licensed by the FDA apart from orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications although some people might of the combinations have been rejected or have yet to be licensed by the FDA.

Seizures are a side effect with Contrave and really should not be taken in people who have seizure disorders. The drug could also raise blood pressure and pulse rate, and must not be used in people who have a history of cardiac arrest or stroke in the earlier six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy while using drug.

The FDA also warned that Contrave can raise blood pressure level and heartbeat and must 't be used in patients with uncontrolled high blood pressure level, in addition to by you are not heart-related and cerebrovascular (circulation dysfunction impacting the mind) disease. Patients with a history of cardiac arrest or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded from your clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes using a boxed warning to alert physicians and patients towards the increased likelihood of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for stopping smoking.


New UCLA study on smokers with mental, drug, and alcohol problems